Table 2.
Association of informative single nucleotide polymorphisms (SNPs) with systemic lupus erythematosus disease status.
| SNP ID | Major allele | Minor allele | Location | P-value | Z-statistic for minor alleles | MAF parents | MAF probands |
|---|---|---|---|---|---|---|---|
| rs12126436 | G | A | 22672978 | 0·27 | 1·10 | 0·12 | 0·14 |
| rs209698 | T | C | 22674119 | 0·17 | 1·35 | 0·33 | 0·35 |
| rs12128546 | T | G | 22682400 | 0·94 | −0·07 | 0·21 | 0·21 |
| rs186037 | T | C | 22697692 | 0·86 | −0·17 | 0·13 | 0·13 |
| rs158761 | G | T | 22699678 | 0·36 | −0·91 | 0·41 | 0·40 |
| rs665691 | G | C | 22705660 | 0·94 | −0·06 | 0·44 | 0·44 |
| rs6690827 | G | A | 22712802 | 0·89 | 0·14 | 0·27 | 0·28 |
| rs12404537 | C | T | 22714674 | 0·66 | −0·43 | 0·19 | 0·18 |
| rs672693 | G | A | 22716752 | 0·72 | −0·35 | 0·33 | 0·32 |
| rs294180 | G | T | 22720100 | 0·33 | −0·96 | 0·38 | 0·36 |
| rs17433222 | G | A | 22723952 | 0·69 | −0·39 | 0·26 | 0·25 |
| rs12040131 | C | G | 22734004 | 0·17 | −1·35 | 0·21 | 0·19 |
| rs7549747 | T | C | 22741877 | 0·96 | −0·06 | 0·43 | 0·44 |
| rs7549888 | G | T | 22749325 | 0·74 | 0·32 | 0·36 | 0·36 |
| rs17486657 | C | T | 22752481 | 0·37 | −0·90 | 0·29 | 0·29 |
| rs294222 | G | G | 22752866 | 1·00 | 0·00 | 0·22 | 0·23 |
| rs294223 | A | C | 22761312 | 0·13 | −1·45 | 0·25 | 0·23 |
| rs17433871 | T | G | 22761409 | 0·77 | −0·38 | 0·25 | 0·25 |
MAF: minor allele frequency.