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Effect of monocyte depletion on Lactobacillus casei Shirota (LcS)-induced CD69 and CD25 expression by peripheral blood mononuclear cells (PBMCs) and monocyte-depleted (MD)-PBMCs. (a) CD69 expression; (b) CD25 expression. PBMCs or MD-PBMCs were incubated with medium or live LcS at 106 colony-forming units (CFU)/ml for 24 h. Data are shown as mean ± standard deviation of 6 to 19 subjects. *P < 0·05, **P < 0·01, ***P < 0·001 compared between PBMC and MD-PBMC cultures.
