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. Author manuscript; available in PMC: 2010 Jul 24.
Published in final edited form as: J Cardiovasc Pharmacol. 2009 Oct;54(4):263–272. doi: 10.1097/FJC.0b013e3181ba0811

FIGURE 1.

FIGURE 1

GJ structure. A, List of all expressed human connexins. B, Topological arrangement of connexin protein monomers. The cylinders represent transmembrane domains and the blue-boxed area represents the highly conserved region among different connexins, whereas the red-boxed area represents the highly divergent region. C, Connexon and GJ channel types. D, Topological arrangement of GJ channels. The GJ channel schematic is superimposed on a transmission electron micrograph of a GJ from canine cardiac tissue. Scale bar = 20 nm.