Table 3.
Stratified analyses for variant pre-miR-146a C/G genotypes in cases and controls
| Variable |
(GG + GC)/CC |
Crude OR (95% CI) | P value | Adjusted OR1 (95% CI) | P value | |
| Cases | Controls | |||||
| Age (median, yr) | ||||||
| ≤ 58 | 105/42 | 93/63 | 1.69 (1.05-2.74) | 0.031 | 1.76 (1.08-2.87) | 0.024 |
| > 58 | 110/47 | 92/56 | 1.42 (0.88-2.29) | 0.145 | 1.43 (0.88-2.33) | 0.147 |
| Sex | ||||||
| Female | 56/20 | 48/28 | 1.63 (0.82-3.26) | 0.164 | 1.80 (0.88-3.67) | 0.105 |
| Male | 159/69 | 137/91 | 1.53 (1.04-2.25) | 0.031 | 1.53 (1.04-2.27) | 0.033 |
| Smoking status | ||||||
| Smokers | 52/21 | 34/21 | 1.53 (0.73-3.22) | 0.263 | 1.49 (0.69-3.21) | 0.310 |
| Non-smokers | 163/68 | 151/95 | 1.51 (1.03-2.20) | 0.035 | 1.55 (1.06-2.28) | 0.025 |
| Residence | ||||||
| Urban | 114/44 | 103/62 | 1.56 (0.98-2.49) | 0.063 | 1.58 (0.98-2.54) | 0.058 |
| Rural | 101/45 | 81/57 | 1.58 (0.97-2.57) | 0.066 | 1.58 (0.96-2.60) | 0.074 |
1
Adjusted for age, sex, smoking status, hypertension, residence and diabetes.