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. Author manuscript; available in PMC: 2010 Jul 26.
Published in final edited form as: J Am Stat Assoc. 2010 Jun 1;105(490):552–563. doi: 10.1198/jasa.2010.ap09258

Table 3.

Probability of observing genotypes given IBD sharing.

Genotypes lj,1, lj,2 IBD=0 IBD=1 IBD=2
AA,AA
P(AAAA)=pA4
P(AAA)=pA3
P(AA)=pA2
AA,AB
2P(AAAB)=2pA3pB
P(AAB)=pA2pB
0
AA,BB
P(AABB)=pA2pB2
0 0
AA,BC
2P(AABC)=2pA2pBpC
0 0
AB,AB
4P(AABB)=4pA2pB2
P(AAB) + (ABB) = pApB(pA + pB) 2P(AB) = 2pApB
AB,AC
4P(AABC)=4pA2pBpC
P(ABC) = pApBpC 0
AB,CD 4P(ABCD) = 4pApBpCpD 0 0