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. Author manuscript; available in PMC: 2010 Jul 26.

Published in final edited form as: J Affect Disord. 2006 Nov 20;100(1-3):91–101. doi: 10.1016/j.jad.2006.10.002

Table 2.

Modeling Age of Onset of first MDD Episode (N=367)

	Univariate Models	Final Multivariate Model
Variables	Hazard Ratio (95% CI)	Hazard Ratio (95% CI)
Perinatal problems	0.98 (0.88, 1.08)	0.96 (.86, 1.06)
Developmental delay	0.96 (0.77, 1.19)	0.87 (.69, 1.10)
Difficult temperament	1.11 (0.99, 1.23)⁺	5.88 (2.05, 16.83)^**
Sex (male = 1)	1.68 (1.36, 2.08)^***	1.75 (1.41, 2.17)^***
Intact family until age 4	0.64 (0.45, 0.91)^*	0.93 (0.58, 1.47)
Mother’s education (years)	0.98 (0.94, 1.01)	--
Maternal age at birth (years)
16-18 vs. 19-34	0.94 (0.60, 1.46)	--
35-46 vs. 19-34	1.73 (1.10, 2.72)^*	--
Temperament X Intact Family	--	0.65 (.45, .92)^*
Temperament X Time	--	0.58 (.37, .92)^*

Note. MDD = major depressive disorder; CI = confidence interval; Cox regression analyses were used.

⁺

p < .07.

^*

p < .05.

^**

p < .01.

^***

p < .001.