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. Author manuscript; available in PMC: 2010 Jul 26.

Published in final edited form as: J Affect Disord. 2006 Nov 20;100(1-3):91–101. doi: 10.1016/j.jad.2006.10.002

Table 3.

Modeling Age of Onset of First Internalizing Disorder Episode (MDD/DD/Anx)

	Univariate Models	Final Multivariate Model
Variables	Hazard Ratio (95% CI)	Hazard Ratio (95% CI)
Perinatal problems	0.98 (0.89, 1.08)	0.95 (0.85, 1.05)
Developmental delay	1.11 (0.89, 1.38)	1.06 (0.84, 1.33)
Difficult temperament	1.22 (1.09, 1.36)^***	4.07 (1.80, 9.20)^***
Sex (male = 1)	1.30 (1.06, 1.60)^*	1.36 (1.10, 1.68)^**
Intact family until age 4	0.77 (0.54, 1.09)	1.01 (.63, 1.60)
Mother’s education (years)	0.99 (.96, 1.02)	--
Maternal age at birth (years)
16-18 vs. 19-34	0.92 (0.59, 1.43)	--
35-46 vs. 19-34	1.58 (1.00, 2.52)⁺	--
Temperament X Intact Family	--	0.65(.45, .93)^*
Temperament X Time	--	0.70 (.49, 1.00)^*

Note. MDD = major depressive disorder; DD = dysthymia; Anx = anxiety disorder; CI = confidence interval; Cox regression analyses were used.

⁺

p < .10.

^*

p < .05.

^**

p < .01.

^***

p < .001.