Table 2.
Comparison of UK and placebo group during treatment
| Factor | UK group (n = 6) | Placebo group (n = 5) | p value |
|---|---|---|---|
| Initial ICP1, mm Hg | 8.3 ± 8.5 | 14.0 ± 13.8 | NS |
| Mean duration of ICP monitoring2, h | 116 ± 30 | 221 ± 172 | NS |
| Mean time of blood clearance from 3rd/4th ventricles2, days | 3.8 ± 1.6 | 10.6 ± 0.6 | 0.02 |
| Mean ICP before clearance of 3rd/4th ventricles2, mm Hg | 10.5 ± 7.7 | 15.6 ± 10.7 | NS |
| Mean ICP after clearance of 3rd/4th ventricles2, mm Hg | 13.0 ± 8.8 | 11.9 ± 7.1 | <0.001 |
| Mean change in ICP from preinjection to 1 h postinjection of study agent2 [ICP(postinj.) – ICP(preinj.)], mm Hg | 3.1 ± 1.0 | 8.2 ± 1.3 | <0.01 |
| Patients with blood cleared from 3rd/4th ventricles1, n | 6/6 | 2/5 | NS |
Values represent mean ± SD or number. SD = Standard deviation; NS = nonsignificant.
1
t test or Fisher's exact test.
2
Wilcoxon rank-sum test.