Table 3.

Logistic regression models for prediction of less favorable outcomes at 3 months

	t-PA treated patients (n = 312)		Placebo (n = 312)
	OR	P	OR	P
Model A: by clinical, laboratory, radiological variables and body weight
Body weight > 100 kg	5.763 (1.356–24.479)	0.017	1.525 (0.581–4.004)	0.392
Hypertension	2.614 (1.177–5.804)	0.018	1.165 (0.637–2.128)	0.621
Baseline NIHSS score	1.205 (1.134–1.281)	<0.001	1.213 (1.148–1.282)	<0.001
Age	1.049 (1.010–1.090)	0.013	1.045 (1.016–1.075)	0.002
Model B: by clinical, laboratory, radiological variables and corrected dose oft-PA
Lower dose oft-PA	1.925 (1.000–3.706)	0.050	n.a.
Hypertension	2.318 (1.143–4.702)	0.020
Baseline NIHSS score	1.190 (1.129–1.254)	<0.001
Age	1.043 (1.010–1.079)	0.014

Figures in parentheses are 95% CI.