Table 2.
Events (%); rate per 10,000 person-years | Absolute rate difference* (per 10,000 person-years) | HR (95% CI) | P value | ||
---|---|---|---|---|---|
Outcomes | Serum potassium 4–4.9 mEq/L (N=522) | Serum potassium <4 mEq/L (N=522) | |||
Mortality | |||||
All-cause | 187 (36%); 1276 | 249 (48%); 1864 | + 587 | 1.56 (1.25–1.95) | <0.001 |
Cardiovascular | 145 (28%); 990 | 204 (39%); 1527 | + 537 | 1.65 (1.29–2.11) | <0.001 |
Progressive HF | 71 (14%); 485 | 111 (21%); 831 | + 346 | 1.82 (1.28–2.57) | <0.001 |
Hospitalization | |||||
All-cause | 358 (69%); 4403 | 376 (72%); 5288 | + 885 | 1.16 (1.00–1.35) | 0.036 |
Cardiovascular | 275 (53%); 2753 | 309 (59%); 3657 | + 904 | 1.27 (1.08–1.50) | 0.004 |
Worsening HF | 177 (34%); 1451 | 203 (39%); 1931 | + 481 | 1.29 (1.05–1.58) | 0.014 |
Absolute differences in rates of events per 10,000 person-year of follow up were calculated by subtracting the event rates in the serum potassium 4–4.9 mEq/L group from the event rates in the serum potassium <4 mEq/L group