Table 4.
Events (%); rate per 10,000 person-years | Absolute rate difference* (per 10,000 person-years) | HR (95% CI) | P value | ||
---|---|---|---|---|---|
Outcomes | Serum potassium 4–4.9 mEq/L (N=65) | Serum potassium <3.5 mEq/L (N=65) | |||
Mortality | |||||
All-cause | 25 (38%); 1276 | 36 (55%); 2236 | + 961 | 2.07 (1.12–3.83) | 0.021 |
Cardiovascular | 19 (29%); 969 | 27 (42%); 1677 | + 708 | 2.09 (1.02–4.29) | 0.044 |
Progressive HF | 9 (14%); 459 | 20 (31%); 1242 | + 783 | 2.83 (1.12–7.19) | 0.028 |
Hospitalization | |||||
All-cause | 52 (80%); 5714 | 55 (85%); 8209 | + 2495 | 1.18 (0.71–1.95) | 0.523 |
Cardiovascular | 44 (68%); 3894 | 44 (68%); 5116 | + 1222 | 1.29 (0.76–2.20) | 0.347 |
Worsening HF | 30 (46%); 1974 | 33 (51%); 2821 | + 847 | 1.24 (0.65–2.34) | 0.517 |
Absolute differences in rates of events per 10,000 person-years of follow-up were calculated by subtracting the event rates in the serum potassium 4 to 4.9 mEq/L group from the event rates in the serum potassium <3.5 mEq/L group.