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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Circ Heart Fail. 2010 Jan 26;3(2):253–260. doi: 10.1161/CIRCHEARTFAILURE.109.899526

Table 5.

Serum potassium <4 mEq/L and outcomes in patients with chronic HF and stage ≥3B CKD (eGFR <45 ml/min/1.73 m2)

Events (%); rate per 10,000 person-years Absolute rate difference* (per 10,000 person-years) HR (95% CI) P value
Outcomes Serum potassium 4–4.9 mEq/L (N=169) Serum potassium <4 mEq/L (N=169)
Mortality
All-cause 80 (47%); 1822 97 (57%); 2487 + 665 1.53 (1.07–2.19) 0.020
Cardiovascular 63 (37%); 1435 79 (47%); 2026 + 591 1.49 (1.00–2.21) 0.049
Progressive HF 25 (15%); 569 53 (31%); 1359 + 790 2.47 (1.41–4.34) 0.002
Hospitalization
All-cause 119 (70%); 5085 135 (80%); 7258 + 2173 1.54 (1.11–2.14) 0.010
Cardiovascular 93 (55%); 3218 109 (64%); 4781 + 1563 1.33 (0.94–1.90) 0.110
Worsening HF 68 (40%); 1960 71 (42%); 2383 + 423 1.26 (0.83–1.93) 0.282
*

Absolute differences in rates of events per 10,000 person-years of follow-up were calculated by subtracting the event rates in the serum potassium 4 to 4.9 mEq/L group from the event rates in the serum potassium <4 mEq/L group.