Table 1.
Population | Disease phenotype | Case/ control | Male/ female | Risk allele frequency |
Genotype |
95% CI |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | χ2 | P-value | OR | Lower | Upper | Powerb | ||||
Argentinian | CED | 180/220 | 156/202 | 0.558 | 0.441 | 61/79/40 | 43/108/69 | 10.92 | 0.00095 | 1.60 | 1.21 | 2.12 | 0.25 |
Colombian | RA | 323/347a | 159/511 | 0.440 | 0.386 | 57/170/96 | 50/168/129 | 3.95 | 0.0469 | 1.25 | 1.00 | 1.55 | 0.38 |
Colombian | T1D | 129/347a | 183/293 | 0.438 | 0.386 | 26/61/42 | 50/168/129 | 2.10 | 0.1469 | 1.24 | 0.93 | 1.66 | 0.24 |
Colombian | pSS | 90/347a | 117/320 | 0.456 | 0.386 | 13/56/21 | 50/168/129 | 2.87 | 0.0905 | 1.33 | 0.96 | 1.85 | 0.20 |
Colombian | SLE | 196/347a | 124/419 | 0.439 | 0.386 | 38/96/62 | 50/168/129 | 2.88 | 0.0899 | 1.24 | 0.97 | 1.60 | 0.30 |
Japanese | SLE | 175/363 | 311/227 | 0.443 | 0.449 | 35/85/55 | 72/182/109 | 0.04 | 0.8485 | 0.98 | 0.76 | 1.26 | 0.29 |
Chinese | SLE | 912/1080 | 424/1397 | 0.378 | 0.338 | 111/344/294 | 107/486/444 | 6.18 | 0.0129 | 1.19 | 1.04 | 1.37 | 0.88 |
aColombian controls are the same for Colombian case–control association analysis; bPower analysis was performed using OR = 1.2, control minor allele frequency = 40% and the number of cases and controls for each population.