Table 2.
Meta-analyses with rs763361 and SLE and T1D
| Risk allele frequency |
95% CI |
Heterogeneity |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Population | Reference | Case/control | Case | Control | OR | Upper | Lower | P-value | χ2 | P-value |
| SLE | ||||||||||
| Pooled | – | – | 1.16 | 1.04 | 1.29 | 0.0086 | 2.19 | 0.3344 | ||
| Colombian | Present | 196/347 | 0.439 | 0.386 | 1.24 | 0.97 | 1.60 | 0.0899 | – | – |
| Chinese | Present | 912/1080 | 0.378 | 0.338 | 1.19 | 1.04 | 1.37 | 0.0129 | – | – |
| Japanese | Present | 175/363 | 0.443 | 0.449 | 0.98 | 0.76 | 1.26 | 0.8485 | – | – |
| T1D | ||||||||||
| Pooled | – | – | 1.14 | 1.09 | 1.18 | 1.46 × 10−9 | 5.68 | 0.1282 | ||
| Estonian | [38] | 154/230 | 0.510 | 0.413 | 1.48 | 1.11 | 1.98 | 0.0084 | – | – |
| Colombian | Present | 129/347 | 0.438 | 0.386 | 1.24 | 0.93 | 1.66 | 0.1469 | – | – |
| UK | [18] | 6021/6088 | 0.504 | 0.469 | 1.15 | 1.09 | 1.21 | 2.82 × 10−8 | – | – |
| UK trio | [18] | 2997 trio | 1396a | 1297b | 1.08 | 0.998 | 1.16 | 0.0281 | – | – |
aTransmitted alleles; bnon-transmitted alleles.