Table 1. Association between T1D and individual SNP genotypes in the 12q13 region.
Logistic regression additive model | ||||||||||
SNP # | SNP Name | Gene | Celera Position | Minor allele | Case freq | Cont freq | p-value | OR | LCL | UCL |
1 | rs3138144 | RDH5 | 55767239 | G | 0.47 | 0.45 | 0.18 | 1.1 | 1.0 | 1.2 |
2 | rs772704 | WIBG | 55968423 | C | 0.17 | 0.19 | 0.04 | 0.9 | 0.8 | 1.0 |
3 | rs1052165 | SILV | 56004000 | T | 0.28 | 0.23 | 5×10−4 | 1.2 | 1.1 | 1.4 |
4 | rs773107 | RAB5B | 56022190 | G | 0.38 | 0.31 | 4×10−9 | 1.4 | 1.2 | 1.5 |
5 | rs705698 | RAB5B | 56037371 | C | 0.38 | 0.32 | 4×10−7 | 1.3 | 1.2 | 1.5 |
6 | rs705702 | SUOX | 56043320 | C | 0.37 | 0.31 | 3×10−6 | 1.3 | 1.2 | 1.4 |
7 | rs10876864 | 3′SUOX | 56053768 | G | 0.47 | 0.42 | 2×10−5 | 1.2 | 1.1 | 1.4 |
8 | rs772921 | 5′IKZF4 | 56056261 | T | 0.38 | 0.32 | 4×10−11 | 1.4 | 1.3 | 1.6 |
9 | rs1701704 | 5′IKZF4 | 56065172 | C | 0.39 | 0.32 | 3×10−9 | 1.4 | 1.2 | 1.5 |
10 | rs2456973 | IKZF4 | 56069619 | G | 0.38 | 0.32 | 6×10−7 | 1.3 | 1.2 | 1.5 |
11 | rs1131017 | RPS26 | 56088616 | C | 0.46 | 0.41 | 1×10−4 | 1.2 | 1.1 | 1.3 |
12 | rs12580100 | 5′ERBB3 | 56091897 | G | 0.13 | 0.12 | 0.43 | 1.1 | 0.9 | 1.2 |
13 | rs11171739 | 5′ERBB3 | 56122295 | C | 0.42 | 0.38 | 4×10−4 | 1.2 | 1.1 | 1.3 |
14 | rs2292239 | ERBB3 | 56133849 | A | 0.38 | 0.32 | 4×10−6 | 1.3 | 1.2 | 1.4 |
15 | rs2292238 | ERBB3 | 56146009 | G | 0.46 | 0.39 | 6×10−8 | 1.3 | 1.2 | 1.5 |
16 | rs4759228 | 5′RPL41 | 56160558 | G | 0.34 | 0.27 | 3×10−9 | 1.4 | 1.3 | 1.6 |
17 | rs12810816 | MYL6 | 56205104 | G | 0.10 | 0.11 | 0.27 | 0.9 | 0.8 | 1.1 |
18 | rs7311008 | SMARCC2 | 56217536 | T | 0.09 | 0.10 | 0.31 | 1.1 | 0.9 | 1.3 |
19 | rs2291738 | TIMELESS | 56468655 | G | 0.49 | 0.47 | 0.43 | 1.0 | 0.9 | 1.2 |
OR: odds ratio, LCL: lower confidence limit, UCL: upper confidence limit.