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(A) Overall representation of the feedback relationships. This network contains interferon γ, STAT1, two AP-1 binding proteins, JUN and FOS, and 37 microRNAs whose predicted promoter regions overlap with STAT1 ChIP-seq regions that contain putative STAT1 and/or AP-1 binding sites. (B) Five instances where STAT1-targeting microRNAs potentially target interferon γ, STAT1, JUN or FOS proteins.
