Table 4.
Published reports of IL1 gene cluster polymorphisms in Chinese population group
| SNPs | Patient (n) | Control (n) | Results | Reference |
|---|---|---|---|---|
| -889C/T (IL1A) |
||||
| 156 POAG | 167 | -889T allele is associated with POAG | Wang et al, Mol Vis, 2006 | |
| 162 NTG | 167 | No association | Wang et al, J of Glaucoma, 2007 | |
| 194 POAG (100 HTG, 94 NTG) and 125 PACG |
79 | No association | How et al, IOVS, 2007 | |
| -511C/T (IL1B) |
||||
| 58 POAG | 105 | No association | Lin et al, Ophthalmologica, 2003 | |
| 231 NTG | 245 | No association | Wang et al, Mol Vis, 2007 | |
| 194 POAG (100 HTG, 94 NTG) and 125 PACG |
79 | No association | How et al, IOVS, 2007 | |
| +3953C/T (IL1B) |
||||
| 58 POAG | 105 | +3953T allele is associated with POAG | Lin et al, Ophthalmologica, 2003 | |
| 231 NTG | 245 | No association | Wang et al, Mol Vis, 2007 | |
| 194 POAG (100 HTG, 94 NTG) and 125 PACG |
79 | No association | How et al, IOVS, 2007 | |