Table 1.
Variable | Grouping | N | (%) |
---|---|---|---|
Age | Mean | 62.51 | |
Minimum | 31 | ||
Maximum | 88 | ||
Stage | I | 54 | (58) |
II | 21 | (23) | |
III | 13 | (14) | |
IV | 5 | (5) | |
Grade | 1 | 28 | (30) |
2 | 47 | (51) | |
3 | 18 | (19) | |
Depth of myometrial invasion | 0 | 3 | (3) |
<50% | 50 | (54) | |
>50% | 40 | (43) | |
Necrosis | Present | 70 | (75) |
Absent | 23 | (25) | |
HIF-1α expression | <1% | 0 | (0) |
≥1% | 93 | (100) | |
<35% | 74 | (80) | |
≥35% | 19 | (20) | |
HIF-1α expression pattern§ | Purely Perinecrotic | 20 | (21) |
Purely Diffuse | 39 | (42) | |
Mixed | 34 | (37) | |
CAIX | Positive | 71 | (76) |
Negative | 22 | (24) | |
Glut-1 | Positive | 76 | (81) |
Negative | 17 | (19) | |
p27kip1 | Positive | 86 | (93) |
Negative | 7 | (7) | |
Follow up time (for surviving patients, in months) | Minimum | 13 | |
Maximum | 182 | ||
Mean | 66 | ||
Recurrence/Metastasis | Yes | 18 | (19) |
No | 72 | (78) | |
Missing | 3 | (3) | |
Survival | Alive | 71 | (76) |
Death of endometrial cancer | 11 | (12) | |
Death of intercurrent disease | 10 | (11) | |
Cause of death unknown | 1 | (1) |
§ Perinecrotic HIF present = mixed and purely perinecrotic HIF pattern grouped.