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. Author manuscript; available in PMC: 2010 Jul 26.
Published in final edited form as: Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):614–632. doi: 10.1080/15257770903091904

TABLE 1.

Relative rates for the North-dAdo and South-dAdo analogues compared to the normal ADA substrates with ADA from calf-intestine (ci) and bovine serum (bs)

ADA (ci)[28]
(50 µM, 37 °C)
ADA (ci)
(60 µM, 25 °C)
ADA (bs)
(60 µM, 25 °C)
Rel. Rates Rel. Rates Rel. Rates
Ado 100 100 100
dAdo 121 124 119
North-dAdo   0.990   1.210   1.380
South-dAdo   0.010   0.007   0.008