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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Neurobiol Dis. 2010 Apr 8;39(3):252–264. doi: 10.1016/j.nbd.2010.03.021

Figure 6. Phrenic nerve hyperstimulation increased cervical spinal cord microgliosis in SOD1G93A rats.

Figure 6

The inflammatory response was examined with the microglial marker, Iba1, in age-matched cervical spinal cords. Immunohistochemistry revealed that compared to wild-type spinal cord (A), there was a significantly elevated microglial response specifically in the ventral gray matter of both SOD1G93A unstimulated (B) and SOD1G93A stimulated (C) SOD1G93A rat groups. The response was significantly increased in SOD1G93A stimulated rats compared to unstimulated SOD1G93A animals (D).