Fig. 2.

Oseltamivir treatment reduces pulmonary virus titers in chronic EtOH exposed and control water mice. Mice were infected and treated with oseltamivir as described in Fig. 1A. On day 2 and day 4 p.i. pulmonary virus was titered by endpoint dilution assay in MDCK cells. On day 4 p.i. there was a significant reduction of viral titers between treated EtOH and untreated EtOH mice p≤0.05 and treated and untreated water mice, p≤0.0001. Data are representative of 1 experiment for day 2 and 2 experiments for day 4 with 3-5 mice per group.