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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Acta Biomater. 2010 Apr 3;6(9):3436–3447. doi: 10.1016/j.actbio.2010.03.038

Figure 3.

Figure 3

Cell viability after endocytosis inhibitor treatment. Cells were plated on uncoated (A), or Col I coated (B) or Fn coated (C) surfaces. Cells were pretreated with the inhibitors for 30 minutes followed by incubation with the DNA/PEI polyplexes for 4 hours in presence of the inhibitors. Cell viability was analyzed at 4 and 48 hours post addition of the polyplexes using the MTT assay. Statistical analysis was done using Dunnett multiple comparison test, which compares each treatment condition to the control. The symbol + and ++ represents the significant change to the level of p < 0.05 and p < 0.01 respectively.