Table 3.
Composite Cardiovascular Events and Mortality
| Temperature Group | |||||
|---|---|---|---|---|---|
| Event or Procedure | Perioda | Hypothermia (499) | Normothermia (501) | P Value | Odds Ratio (95% Confidence Interval) |
| Any Cardiovascular Event | Perioperative | 188 (38%) | 164 (33%) | 0.11 | 1.24 (0.96 - 1.61) |
| Postoperative | 196 (39%) | 208 (42%) | 0.48 | 0.91 (0.71 - 1.17) |
|
| Any Vasopressor Administration | Perioperative | 132 (26%) | 118 (24%) | 0.31 | 1.17 (0.88 - 1.55) |
| Postoperative | 116 (23%) | 105 (21%) | 0.40 | 1.14 (0.85 - 1.54) |
|
| Any “Indicator” Cardiovascular Event | Perioperative | 44 (9%) | 42 (8%) | 0.82 | 1.06 (0.68 - 1.64) |
| Postoperative | 31 (6%) | 23 (5%) | 0.27 | 1.38 (0.79 - 2.30) |
|
| Any Cardiovascular Event | Perioperativeb | 8 (2%) | 6 (1%) | 0.60 | 1.34 (0.46 - 3.90) |
| Rated Severe or Fatal | Postoperativec | 24 (5%) | 37 (7%) | 0.11 | 0.64 (0.37 - 1.08) |
| Myocardial Infarction, Congestive Heart Failure or Pulmonary Edema, Ventricular Arrhythmia, Cardioversion or Defibrillation | Either Perioperative or Postoperative | 62 (12%) | 64 (13%) | 0.92 | 0.97 (0.67 - 1.41) |
| Mortality (any cause) | Either Perioperative or Postoperativec | 29 (6%) | 32 (6%) | 0.79 | 0.90 (0.54 - 1.52) |
All P values calculated using Fisher's Exact test.
All odds ratios calculated with normothermia as the reference group.
a
Perioperative events had their onset during surgery or during the first 2 h after surgery. Postoperative events had their onset more than 2 h after surgery until final 3-month follow-up.
b
In the perioperative period, one patient had intraoperative cardiac arrest and death, see Results for details. In the perioperative period the most common events rated as severe (but nonfatal) were vasopressor, systemic (n = 7), hypertension, not intended (n = 4), and vasopressor, cerebral (n = 2).
c
See Results regarding postoperative deaths.