Table 4.
Genotype distribution of IL-6rα, Los-Angeles County, 1999–2002 | |||
---|---|---|---|
IL-6rα | Case | Relative-Control | Case/relative used for Cozen et al. |
DD | 55 | 50 | 36/39 |
DA+AA | 55+11 | 37+14 | 46/43 |
Missing | 29 | 11 | 68/30 |
Total | 150 | 112 | 150/112 |
Odds Ratio estimates for the association of IL-6rα and the risk of multiple myeloma | |||
Method | OR | ASE | 95% CI |
CCA | 1.80 | 0.464 | (0.70, 4.50) |
SMI | 2.95 | 0.174 | (2.10, 4.16) |
MMI1 | 1.92 | 0.219 | (1.25, 2.95) |
MMI2 | 2.14 | 0.191 | (1.47, 3.42) |
MI | 2.08 | 0.171 | (1.49, 2.91) |
ASE, asymptotic standard error; CI, confidence interval; CCA, complete case analysis adjusted for education level, BMI, and age as in Cozen et al., 2006; SMI, single missing indicator; MMI, modeled missing indicator; MMI1, MMI with interaction between missing indicator and gender; MMI2, MMI with interaction between missing indicator and race (white/black); MI, multiple imputation.
Note: From the total of 112 pairs CCA uses 82 complete pairs