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. Author manuscript; available in PMC: 2010 Sep 21.
Published in final edited form as: Biometrics. 2010 Sep;66(3):845–854. doi: 10.1111/j.1541-0420.2009.01322.x

Table 4.

Genotype distribution and analysis results of the association between multiple myeloma and IL-6rα, Los-Angeles County, 1999–2002

Genotype distribution of IL-6rα, Los-Angeles County, 1999–2002

IL-6rα Case Relative-Control Case/relative used
for Cozen et al.
DD 55 50 36/39
DA+AA 55+11 37+14 46/43
Missing 29 11 68/30
Total 150 112 150/112
Odds Ratio estimates for the association of IL-6rα and the risk of multiple myeloma

Method OR ASE 95% CI

CCA 1.80 0.464 (0.70, 4.50)
SMI 2.95 0.174 (2.10, 4.16)
MMI1 1.92 0.219 (1.25, 2.95)
MMI2 2.14 0.191 (1.47, 3.42)
MI 2.08 0.171 (1.49, 2.91)

ASE, asymptotic standard error; CI, confidence interval; CCA, complete case analysis adjusted for education level, BMI, and age as in Cozen et al., 2006; SMI, single missing indicator; MMI, modeled missing indicator; MMI1, MMI with interaction between missing indicator and gender; MMI2, MMI with interaction between missing indicator and race (white/black); MI, multiple imputation.

Note: From the total of 112 pairs CCA uses 82 complete pairs