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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Aging Cell. 2010 Jun 17;9(4):607–615. doi: 10.1111/j.1474-9726.2010.00583.x

Figure 2. The dosage of smoking is directly associated with the expression of serum markers of telomere dysfunction and DNA damage.

Figure 2

(A–C) The Regression analysis shows the correlation of tobacco smoking (measured in pack years: 1 pack per day for 1 year = 1 pack year) with (A) the best combination of serum markers of telomere dysfunction and DNA damage (combination score equals to 0.0942 × stathmin +7.2519 × chitobiosidase), (B) with the expression of P16INK4a mRNA in PBTLs, and (C) with telomere length in PBTLs. The black line shows the regression line and the dashed lines the 95% confidence bands for the regression line.