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. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: J Alzheimers Dis. 2010 Jan;21(1):75–79. doi: 10.3233/JAD-2010-091603

Figure 1.

Figure 1

Charts shows the results of 19 cases evaluated, correlating the normalized expression of miR-107 with neuritic plaque lesion density counts in adjacent tissue sections from superior-mid temporal cortical (SMT) gyri (A) and BACE1 mRNA levels (B). There is a trend for decreased miR-107 in cases with more neuritic plaques (regression P<0.05). Note, however, that there were cases (red arrow) with low miR-107 expression despite lacking any SMT neuritic plaques. The negative correlation between miR-107 and BACE1 mRNA levels does not reach statistical significance (P<0.07).