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. 2010 Jun 8;29(14):2358–2367. doi: 10.1038/emboj.2010.122

Figure 1.

Figure 1

Schematic structure of Dis3 and Dis3-like proteins in yeast and human beings. Schematic diagram of S. cerevisiae Dis3 (yDis3), human Dis3 (hDis3), human Dis3-like 1 (hDis3L1) and human Dis3-like 2 (hDis3L2) with the identified domains indicated: the PIN domain, two cold shock domains (CSD1, CSD2), an RNB domain and an S1 RNA-binding domain. Crackled boxes and question marks indicate domains with a low level of conservation (see Supplementary Figure S1 for details). The level of sequence similarity between the human Dis3 proteins and yDis3 is indicated on the right.