Fig. 5.

Map of the rat NKC. Arrows indicate gene orientation. Numbers below the line indicate distance from the starting point (the Nkrp1a gene at 165.637 Mb according to the current release of the rat genome). The four major clusters are color-coded: green Nkrp1/Clr gene cluster (including Cd69 and Clec2m), magenta Clec12a–Lox1 cluster, red Klre1–Klri2 cluster, blue Ly49 cluster. The topography of the chromosomal map with respect to major clusters is seen to be congruent with the major branches of the phylogenetic tree in Fig. 4. It should be emphasized that most of the genes shown here have been cDNA cloned primarily in the DA or PVG strain, so that the map shown here represents the positions of the predicted alleles from the BN strain, from which the rat genome sequence is derived. The extent of intestrain variation, including copy number variation, is so far largely uncharted