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. 2009 Jun 30;24(11):3366–3371. doi: 10.1093/ndt/gfp316

Table 5.

Logistic regression results T2DM ESRD versus T2DM non-nephropathy controls—MYH9 haplotypes, age and gender adjusted

Haplotype frequency No admixture adjustment Admixture adjustment
Haplotype Model Case Control P-value OR 95% CI P-value OR 95% CI
E1 haplotype consisting of SNPs: rs4821480— rs2032487—rs4821481—rs3752462
3224 Dominant 0.63 0.58 0.6619 1.10 (0.73, 1.65) 0.9083 0.98 (0.64, 1.48)
Additive 0.1081 1.19 (0.96, 1.48) 0.3213 1.12 (0.90, 1.39)
Recessive 0.0479 1.38 (1.00, 1.89) 0.1308 1.28 (0.93, 1.77)
4442 Dominant 0.20 0.22 0.0991 0.77 (0.57, 1.05) 0.2606 0.84 (0.61, 1.14)
Additive 0.4091 0.90 (0.69, 1.16) 0.8426 0.97 (0.74, 1.27)
Recessive 0.1076 2.20 (0.84, 5.72) 0.0428 2.74 (1.03, 7.26)
4444 Dominant 0.13 0.18 0.0504 0.72 (0.51, 1.00) 0.0799 0.74 (0.53, 1.04)
Additive 0.0232 0.72 (0.54, 0.96) 0.0425 0.74 (0.56, 0.99)
Recessive 0.0702 0.45 (0.19, 1.07) 0.1083 0.49 (0.20, 1.17)
L1 haplotype consisting of SNPs: rs7078—rs12107—rs735853—rs5756129
1324 Dominant 0.63 0.59 0.2865 1.25 (0.83, 1.89) 0.4693 1.17 (0.77, 1.77)
Additive 0.1681 1.17 (0.94, 1.45) 0.3361 1.12 (0.89, 1.39)
Recessive 0.2390 1.21 (0.88, 1.66) 0.4055 1.15 (0.83, 1.57)
1334 Dominant 0.80 0.90 0.7211 0.93 (0.61, 1.40) 0.8550 1.04 (0.68, 1.59)
Additive 0.9353 0.98 (0.67, 1.44) 0.6249 1.10 (0.75, 1.63)
Recessive 0.3516 2.63 (0.34, 20.03) 0.2460 3.36 (0.43, 25.99)