Table 5.
Logistic regression results T2DM ESRD versus T2DM non-nephropathy controls—MYH9 haplotypes, age and gender adjusted
| Haplotype frequency | No admixture adjustment | Admixture adjustment | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Haplotype | Model | Case | Control | P-value | OR | 95% CI | P-value | OR | 95% CI |
| E1 haplotype consisting of SNPs: rs4821480— rs2032487—rs4821481—rs3752462 | |||||||||
| 3224 | Dominant | 0.63 | 0.58 | 0.6619 | 1.10 | (0.73, 1.65) | 0.9083 | 0.98 | (0.64, 1.48) |
| Additive | 0.1081 | 1.19 | (0.96, 1.48) | 0.3213 | 1.12 | (0.90, 1.39) | |||
| Recessive | 0.0479 | 1.38 | (1.00, 1.89) | 0.1308 | 1.28 | (0.93, 1.77) | |||
| 4442 | Dominant | 0.20 | 0.22 | 0.0991 | 0.77 | (0.57, 1.05) | 0.2606 | 0.84 | (0.61, 1.14) |
| Additive | 0.4091 | 0.90 | (0.69, 1.16) | 0.8426 | 0.97 | (0.74, 1.27) | |||
| Recessive | 0.1076 | 2.20 | (0.84, 5.72) | 0.0428 | 2.74 | (1.03, 7.26) | |||
| 4444 | Dominant | 0.13 | 0.18 | 0.0504 | 0.72 | (0.51, 1.00) | 0.0799 | 0.74 | (0.53, 1.04) |
| Additive | 0.0232 | 0.72 | (0.54, 0.96) | 0.0425 | 0.74 | (0.56, 0.99) | |||
| Recessive | 0.0702 | 0.45 | (0.19, 1.07) | 0.1083 | 0.49 | (0.20, 1.17) | |||
| L1 haplotype consisting of SNPs: rs7078—rs12107—rs735853—rs5756129 | |||||||||
| 1324 | Dominant | 0.63 | 0.59 | 0.2865 | 1.25 | (0.83, 1.89) | 0.4693 | 1.17 | (0.77, 1.77) |
| Additive | 0.1681 | 1.17 | (0.94, 1.45) | 0.3361 | 1.12 | (0.89, 1.39) | |||
| Recessive | 0.2390 | 1.21 | (0.88, 1.66) | 0.4055 | 1.15 | (0.83, 1.57) | |||
| 1334 | Dominant | 0.80 | 0.90 | 0.7211 | 0.93 | (0.61, 1.40) | 0.8550 | 1.04 | (0.68, 1.59) |
| Additive | 0.9353 | 0.98 | (0.67, 1.44) | 0.6249 | 1.10 | (0.75, 1.63) | |||
| Recessive | 0.3516 | 2.63 | (0.34, 20.03) | 0.2460 | 3.36 | (0.43, 25.99) | |||