Table 2.
Urine creatinine clearance versus creatinine clearance estimated by Cockcroft–Gault, MDRD, Jelliffe and Modified Jelliffe equations in 12 patients
| Creatinine used for calculation | First day | Mean | Second day |
|---|---|---|---|
| Serum creatinine (mg/dL) | 3.6 ± 1.5 | 3.8 ± 1.6 | 4.0 ± 1.7 |
| Cockcroft–Gault (mL/min) | 24.9 ± 12.8 | 23.7 ± 12.4* | 22.5 ± 12.1 |
| Cockcroft–Gault (mL/min/1.73 m2) | 22.5 ± 10.9 | 21.4 ± 10.6 | 20.3 ± 10.3 |
| MDRD (mL/min/1.73 m2) | 18.3 ± 7.3 | 17.3 ± 7.2* | 16.3 ± 7.1 |
| Jelliffe (mL/min/1.73 m2) | 15.7 ± 10.0 | ||
| Modified Jelliffe (mL/min/1.73 m2) | 14.4 ± 9.3 | ||
| Urine creatinine clearance (mL/min) | 16.1 ± 7.1 | 15.4 ± 7.1 | 14.8 ± 7.1 |
| Urine creatinine clearance adjusted for BSA (mL/min/1.73 m2) | 14.6 ± 6.1 | 14.0 ± 6.1 | 13.4 ± 6.1 |
*We reported the mean of the two glomerular filtration rate (GFR)s for Cockcroft–Gault and MDRD. When using the mean creatinine of the first day and second day, instead of the mean of the two GFRs, the results were very similar (for Cockcroft–Gault: 23.6 ± 12.4 mL/min when using the mean creatinine versus 23.7 ± 12.4 mL/min when using the mean GFR and for MDRD, 17.2 ± 7.2 mL/min/1.73 m2 when using the mean creatinine versus 17.3 ± 7.2 mL/min/1.73 m2 when using the mean GFR).
MDRD, Modification of Diet in Renal Disease; BSA, body surface area.