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. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: Neuropsychobiology. 2008 Oct 3;58(2):81–90. doi: 10.1159/000159776

c Tukey simultaneous tests: all pairwise comparisons among types of rat for statistically significant pharmacokinetic parameters

Parameter Pairwise comparison of means p value
AUC, min × ng/ml HAD-1 vs. LAD-1 0.1204 (not significant)
HAD-1 vs. Wistar 0.0105 (highly significant)
LAD-1 vs. Wistar 0.3315 (not significant)

AUC_D, min × kg × ng/ml/mg HAD-1 vs. LAD-1 0.1204 (not significant)
HAD-1 vs. Wistar 0.0105 (highly significant)
LAD-1 vs. Wistar 0.3315 (not significant)

Cl, ml/min/kg HAD-1 vs. LAD-1 0.2174 (not significant)
HAD-1 vs. Wistar 0.0051 (highly significant)
LAD-1 vs. Wistar 0.1079 (not significant)

When a significant difference was found, Tukey simultaneous tests were employed. AUC = Area under the blood level-time curve; AUC_D= dose-normalized AUC; Cl = clearance.