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. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: Neuropsychopharmacology. 2007 Oct 3;33(1):42–55. doi: 10.1038/sj.npp.1301554

Figure 3.

Figure 3

Acute amphetamine exerts differential effects on mPFC and OFC ensemble unit activity. (a–b) Representative firing rate histograms of individual neurons responding to acute systemic amphetamine (2 mg/kg). Arrow indicates the time of injection and dashed line signifies change from pre-injection baseline. Acute amphetamine inhibited the mPFC neuron (a) but excited the OFC neuron (b). (c) Population firing rate response (mean±SEM) of all neurons in each region to acute amphetamine. Acute amphetamine caused an excitatory response in OFC and an inhibitory response to mPFC (adapted from Homayoun and Moghaddam, 2006).