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. 2010 Apr 13;3(4):1093–1107. doi: 10.3390/ph3041093

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© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Translocation of IpTxa from external to intracellular compartments of intact mouse ventricular myocytes. All images represent the transmitted light image of the cardiomyocytes (C and B also show Fluo-3 fluorescence). A, C, and E were imaged at the beginning of the protocol, before the start of Alexa-IpTxa perfusion. B, Same cell as A, but after 10 minutes of Alexa-maleimide (1 μM) perfusion. D, Same cell as C, but after 10 minutes of Alexa-IpTxa (1 μM) perfusion. F, Same cell as E, but after 30 minutes of Alexa-IpTxa (1 μM) perfusion.