Table 1.
Type of Malignancy | Claudin gene | Expression | |
---|---|---|---|
Breast Carcinoma | CLDN1 | Down | |
CLDN3 | Up | ||
CLDN4 | Up | ||
CLDN7 | Down | ||
Biliary tract Carcinoma | CLDN4 | Up | |
Colorectal Carcinoma | CLDN1 | Up | |
CLDN8 | Down | ||
CLDN12 | Up | ||
Endometrial endometrioid Carcinoma | CLDN1 | Down | |
CLDN2 | Up | ||
Endometrial seropapillary Carcinoma | CLDN1 | Up | |
CLDN2 | Down | ||
Gastric adenocarcinoma | CLDN1 | Up | |
CLDN3 | Up | ||
CLDN4 | Up | ||
CLDN5 | Up | ||
Hepatocellular carcinoma | CLDN4 | Down | |
CLDN7 | Up | ||
Hepatoblastoma (Fetal) | CLDN1 | Up | |
CLDN2 | Up | ||
CLDN3 | Down | ||
CLDN4 | Down | ||
CLDN7 | Down | ||
Head & Neck (SCC) | CLDN7 | Down | |
Lung cancer (Adenocarcinoma) | CLDN1 | Down | |
CLDN5 | Up | ||
Lung cancer (SCC) | CLDN1 | Up | |
CLDN5 | Down | ||
Meningioma | CLDN1 | Up | |
Mesothelioma | CLDN4 | Down | |
CLDN5 | Down | ||
Metastatic Melanoma | CLDN1 | Down | |
Oncocytoma | CLDN7 | Down | |
CLDN8 | Up | ||
Ovarian epithelial Carcinoma | CLDN1 | Up | |
CLDN3 | Up | ||
CLDN4 | Up | ||
CLDN5 | Up | ||
CLDN7 | Up | ||
Ovarian sex cord stromal Tumors | CLDN1 | Down | |
CLDN3 | Down | ||
CLDN4 | Down | ||
CLDN5 | Down | ||
Pancreatic Carcinoma | CLDN1 | Up | |
CLDN4 | Up | ||
Pleura (metastatic adenocarcinoma) | CLDN3 | UP | |
CLDN4 | UP | ||
Prostate Carcinoma | CLDN1 | Up | |
CLDN2 | Down | ||
CLDN3 | Up | ||
CLDN4 | Up | ||
CLDN5 | Down | ||
CLDN7 | Up | ||
Renal cell Carcinoma | CLDN1 | Up | |
CLDN3 | Up | ||
CLDN4 | Up | ||
Renal cell Carcinoma (Chromobhobe) | CLDN7 | Up | |
Tongue (SCC) | CLDN1 | Up | |
CLDN4 | Up | ||
CLDN7 | Up | ||
Thyroid Carcinomas | CLDN1 | Up | |
CLDN4 | Up | ||
CLDN7 | Up | ||
Undifferentiated Thyroid Carcinoma | CLDN1 | Down |