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. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: Neuropharmacology. 2008 Nov 7;56(2):541–555. doi: 10.1016/j.neuropharm.2008.10.012

Figure 3. Effect of EtOH on action potential number and Em in layer II and layer III pyramidal neurons.

Figure 3

(A) Representative current-clamp traces obtained in the perforated-patch configuration illustrating responses to injection of 50 pA for 100 ms in layer II. (B) Summary of action potential number and estimated Em for the indicated experimental conditions. Layer II: action potential (filled circle), Em (open circle), n=8 cells; layer III: action potential (filled square), Em (open square), n=7. *** p< 0.001 by one-way ANOVA followed by Tukey’s post-hoc test. (C–D) Same as in A and B but in the presence of picrotoxin (50 μM) and gabazine (10 μM) (n=3 cells per layer).