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. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: Neuropharmacology. 2008 Nov 7;56(2):541–555. doi: 10.1016/j.neuropharm.2008.10.012

Figure 5. ECl and Em in layer II and layer III pyramidal neurons.

Figure 5

(A, C) Voltage-clamp traces illustrating currents evoked by pressure application of muscimol (300 μM for 100 ms) at the indicated holding potentials in the gramicidin perforated-patch configuration. (B, D) Peak current-voltage relationships from experiments shown in A and C. Estimated Em values were determined in the current-clamp mode. (E) Estimated Em and ECl− from 6 layer II (filled circle) and 6 layer III (open square) pyramidal neurons.