Skip to main content
. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: Circulation. 2004 Apr 5;109(16):2023–2029. doi: 10.1161/01.CIR.0000127034.50006.C0

Figure 3.

Figure 3

In vivo visualization of subacute thrombosis after plaque rupture induced by RVV and histamine. A, On the pretrigger baseline image, no apparent thrombosis is visible. B, At 24 hours after trigger, a gray mass (arrow) overlying the vessel wall can be observed, suggestive of a mural thrombus. C, Thirty minutes after EP-1873 injection, a bright rim (arrow) becomes visible along the lumen-facing surface of this mass, which subsequently increased in size and signal intensity, as shown at 60 minutes (D). E, Twenty hours after EP-1873 injection, entire mass (arrow) appeared bright and well defined, suggesting that the fibrin-binding agent had completely penetrated the thrombus. Good agreement was found with thrombus (arrows) on histopathology (F).