Table 4. Association of ERP with all-cause mortality.

Study Population	Substrata	ERP in any Localization		ERP in Inferior Localization
		HR (95% CI)	p-Value	HR (95% CI)	p-Value
All
Main effect	ERP	1.87 (1.03–3.37)	0.038	2.17 (1.11–4.23)	0.023
	ERP × age	0.97 (0.95–1.00)	0.041	0.98 (0.95–1.01)	0.11
Age-strata	35–54 y	1.39 (0.95–2.03)	0.095	1.80 (1.15–2.81)	0.010
	55–64 y	1.00 (0.71–1.40)	0.98	1.18 (0.79–1.77)	0.41
	65–74 y	0.77 (0.41–1.45)	0.42	0.13 (0.58–2.20)	0.71
Women
Main effect	ERP	2.05 (0.62–6.82)	0.24	1.24 (0.30–5.17)	0.77
	ERP × age	0.96 (0.91–1.01)	0.12	0.99 (0.93–1.05)	0.63
Age-strata	35–54 y	0.97 (0.49–1.91)	0.92	0.94 (0.42–2.08)	0.88
	55–64 y	0.74 (0.37–1.48)	0.40	1.00 (0.44–2.28)	1.00
	65–74 y	0.60 (0.23–1.56)	0.30	0.51 (0.16–1.69)	0.27
Men
Main effect	ERP	1.67 (0.85–3.30)	0.14	2.62 (1.24–5.57)	0.012
	ERP × age	0.98 (0.95–1.01)	0.26	0.97 (0.94–1.01)	0.15
Age-strata	35–54 y	1.88 (1.15–3.08)	0.012	2.80 (1.61–4.88)	<0.001
	55–64 y	1.11 (0.74–1.67)	0.61	1.35 (0.83–2.20)	0.23
	65–74 y	1.02 (0.42–2.48)	0.96	1.55 (0.58–4.13)	0.29

Association of ERP with all-cause mortality is displayed for both ERP and for an ERP localization restricted to inferior leads. Results are shown for the entire study population, and separated for women and men. Results for the main effect are derived from a weighted Cox-proportional hazards model-based pooled analysis of the entire study population, incorporating an ERP-age interaction term (ERP × age) to account for age-dependence of ERP. Results for three different age-strata are shown. All calculations are adjusted for sex, age, and survey and for the following clinical covariables: body mass index, total cholesterol/HDL cholesterol ratio, arterial hypertension, nicotine abuse, congestive heart failure, prior myocardial infarction, diabetes mellitus, heart rate, and QTc. In case of age- and/or sex-stratified analyses, no further adjustment was performed for the respective variables.