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. Author manuscript; available in PMC: 2011 Apr 20.
Published in final edited form as: Dev Cell. 2010 Apr 20;18(4):662–674. doi: 10.1016/j.devcel.2010.02.014

Figure 1.

Figure 1

MyoD binding in C2C12 myotubes. A) Average number of each E-box sequence under myotube peaks and control regions, where 1.0 indicates that each peak has on average one E-box of that sequence. Reverse complement sequences were combined. Compared to the controls, myotubes are enriched for CAGCTG and CAGGTG/CACCTG. B) Myotube peaks are enriched for 5’ A/G and depleted for 3’A at the positions immediately flanking the E-box (CAG[C/G]TG). The size of each nucleotide at a given position is proportional to the frequency of the nucleotide at that position. The darkness of the line connecting the two adjacent nucleotides is determined by the corresponding dinucleotide frequency. The counts of patterns on both strands are indicated above the graphs. C) Motifs enriched in E-box containing Myod binding regions in C2C12 myotube peaks. D) Motifs enriched in non-E-box containing MyoD binding regions in C2C12 myotube peaks.