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Nyctohemeral variation of hormone serum levels. x-y plot showing 24-hour time qualified profiles of cortisol, melatonin, TRH, TSH, free thyroxine, GH and IGF 1 expressed as mean ± s.e. calculated on single time point values from ten healthy subjects and ten patients suffering from non small cell lung cancer. Cubic regression function data interpolation represented as best fit solid line superimposed on the raw data (dotted line).
