. Author manuscript; available in PMC: 2010 Jul 27.

Published in final edited form as: J Nat Prod. 2007 Jan;70(1):130–133. doi: 10.1021/np0604883

Table 3.

IC₅₀ Values (μM) of 1 and 2 on Tumor Cell^a Proliferation/Viability Under Hypoxic (Hyp)^b and Normoxic (Norm)^c Conditions.

		1	2
DU145	Hyp	> 30	5.3
	Norm	> 30	6.6
PC-3	Hyp	> 30	12.9
	Norm	> 30	16.7
MCF-7	Hyp	> 30	6.6
	Norm	> 30	13.8
MDA-MB-231	Hyp	17.8	5.6
	Norm	17.8	13.3
T47D	Hyp	26.9	6.0
	Norm	14.7	5.6

Cell lines: DU145 and PC-3, prostate cancer; MCF-7, MDA-MB-231, and T47D, breast cancer.

Hypoxic condition: 1% O₂:94% N₂:5% CO₂, 48 h.

Normoxic condition: 95% Air:5% CO₂, 48 h. The IC₅₀ values were determined from one experiment performed in quadruplicate, and the standard deviation for each data point is less than 10%.