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. Author manuscript; available in PMC: 2010 Jul 27.
Published in final edited form as: J Nat Prod. 2004 Dec;67(12):2002–2007. doi: 10.1021/np049753f

Figure 2.

Figure 2

Compound 1 inhibits hypoxia-induced HIF-1 activation in T47D cells (A). Effect of 1 (3 μM) on HIF-1 activation by a hypoxia mimetic 1,10-phenanthroline (10 μM) in T47D cells (B). Data shown are means from one representative experiment performed in quadruplicate and the bars represent standard error. In (B), an asterisk (*) indicates a significance of p < 0.001 when compared to the control, and lack of asterisk indicates no statistical difference (ANOVA and Fisher's PLSD post hoc test).