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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Thromb Res. 2010 Aug;126(2):130–136. doi: 10.1016/j.thromres.2010.04.010

Fig 2. Heterogeneity in F.II mRNA 3′-end formation.

Fig 2

Constitutively expressed βF.IIG or βF.IIA mRNAs from representative HepG2 cell lines were subjected to 3′ cleavage-site analysis. The frequency of polyadenylation at each of eight sites is indicated. mRNAs terminating at sites encoded by vector sequence (vect) or specifying mutant sequence (mut) are indicated. F.IIG 3′UTRs that undergo 3′-cleavage/polyadenylation at positions 20210G and 20211A produce identical sequences, as do F.IIA 3′UTRs that are processed at positions 20209C, 20210A, and 20211A. In both instances, transcripts are categorized as 20210-terminal mRNAs.