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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Stem Cells. 2010 Jul;28(7):1186–1195. doi: 10.1002/stem.437

Figure 3.

Figure 3

Fancd2-deficient bone marrow contains reduced functional hematopoietic activity. (A, B) Decreased progenitor activity (CFU-C and day 7 CAFC) in the Fancd2−/− bone marrow compared to the wild-type bone marrow. (C): Significant reduction in the primitive HSC activity (day 28 CAFC) in the bone marrow of Fancd2−/− mice compared to the bone marrow of wild-type mice. Data in all the plots are average from n = 4 Wild-type mice and n = 4 Fancd2−/− mice. Error bars indicate SEM. The p values for the difference between wild-type and Fancd2−/− groups in the plots A, B, and C were 0.005, 0.172, and 0.022, respectively. Abbreviations: CAFC, cobblestone area-forming cell; CFU-C, colony-forming units in culture.