. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2009 Jun 16;239(2):200–207. doi: 10.1016/j.taap.2009.06.007

Table 3.

The effects of AS3MT polymorphisms on the distribution of As metabolites in urine (n=122).

SNPs	% iAs^lll+V	% MAs^lll+V	% DMAs^lll+V	MAs^lll+V/iAs^lll+V	DMAs^lll+V/MAs^lll+V	% iAs^V	% MAs^V	% DMAs^V
A-477G
Genotype frequency	18	11	71	0.8	8.7	9.2	3.3	23.9
AA/AG (0.85)	13^*	9^**	78^**	0.7	10.8^**	8.0	2.1^*	23.8
GG (0.15)
Allelic frequency
A (0.62)	18	11	71	0.8	8.7	9.2	3.3	23.9
G (0.38)	17	10	73	0.7	10.0^**	8.8	2.5	23.8
Met287Thr
Genotype frequency
TT (0.88)	17	10	73	0.7	9.4	8.5	3.1	23.5
CT/CC (0.12)	21^*	15^**	64^*	0.7	6.1^*	13.4^**	2.7	26.7
Allelic frequency
T (0.934)	17	11	72	0.7	9.0	9.1	3.1	23.5
C (0.066)	21	15^**	64^**	0.7	6.1^*	13.4^**	2.7	26.7
T35587C
Genotype frequency
TT (0.58)	18	12	70	0.7	8.5	9.9	3.1	22.8
CT (0.42)	16	10	74	0.8	9.8	8.1	3.2	25.5
Allelic frequency
T (0.79)	17	11	72	0.7	9.0	9.1	3.1	23.9
C (0.21)	16	10	74	0.8	9.8	8.1	3.2	25.5

Student t-test.

Significance is shown in footnote of corresponding tables (p<0.05).

p<0.1.

^**

p<0.05.