. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2009 Jun 16;239(2):200–207. doi: 10.1016/j.taap.2009.06.007

Table 7.

Arsenic metabolism and extended AS3MT haplotype frequencies in the study population.

Haplotypes	1(ATT)	2(GTT)	3(ACT)	4(ATC)	5(ACC)	6(GCT)	7(GCC)
N	100	72	9	34	1	13	5
% iAs^lll+V	17.7	16.9	25	16.6	19.9	21	14.3
% MAs^lll+V	11.3^a	10.2^a	19	10.2^a	9.2	16	9
% DMAs^lll+V	71^a	72.9^a	56	73.2^a	70.1	63	76.7
MAs^lll+V/iAs^lll+V	0.77	0.74	0.77	0.89	0.46	0.76	0.66
DMAs^lll+V/MAs^lll+V	8.7	10	4.5	9.8	7.7	6	8.8
% iAs^V	9.2^a,^b	8.8^a,^b	14.5	8.0^a,^b	15	12.6	10.3
% iAs^III	8.5	8.1	10.2	8.6	5	8.4	4
% MAs^V	3.3	2.5	3.3	3.6	2	2.2	1.6
% MAs^III	8^a	7.7^a	15.5	6.6^a	7	13.5	7.3
% DMAs^V	23.4	23.8	30.5	25	12.4	22.4	20.6
% DMAs^III	47.6^a	49.1^a	26	48.2^a	58.6	40.9	56.2

Values are a geometric mean of each arsenic metabolite.

Compared with 3(ACT) haplotype.

Compared with 6(GCT) haplotype, significant at p<0.05, using ANOVA and the Holm–Sidak test.