Table 3.
Treatment Group |
Overall Treatment Effect |
Specific Treatment Effect |
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Whole Sample |
Haloperidol (n = 23) |
Risperidone (n = 52) |
Olanzapine (n = 25) |
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Neuromotor Domain | Baseline | 4 Wk | Baseline | 4 Wk | Baseline | 4 Wk | Baseline | 4 Wk | F1 | P | F2 | P |
Parkinsonism | 2.34 ± 3.61 | 3.62 ± 4.10 | 2.39 ± 4.09 | 4.04 ± 4.11 | 1.69 ± 2.93 | 3.81 ± 4.36 | 3.64 ± 4.19 | 2.84 ± 3.55 | 9.87 | .002 | 2.78 | .067 |
Dyskinesia | 0.37 ± 0.88 | 0.20 ± 0.55 | 0.57 ± 1.16 | 0.30 ± 0.63 | 0.21 ± 0.69 | 0.12 ± 0.47 | 0.52 ± 0.91 | 0.28 ± 0.61 | 4.94 | .001 | 0.29 | .750 |
Akathisia | 0.12 ± 0.53 | 0.43 ± 0.92 | 0.43 ± 1.03 | 1.13 ± 1.32 | 0.04 ± 0.19 | 0.31 ± 0.75 | 0.00 ± 0.00 | 0.04 ± 0.20 | 9.97 | .002 | 9.32 | < .001a |
Catatonia | 2.98 ± 5.28 | 0.94 ± 2.32 | 2.61 ± 4.37 | 0.65 ± 1.33 | 3.08 ± 5.87 | 1.12 ± 2.74 | 3.12 ± 4.92 | 0.84 ± 2.11 | 21.36 | < .001 | 0.32 | .723 |
Haloperidol > risperidone, olanzapine.