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. Author manuscript; available in PMC: 2010 Jul 28.
Published in final edited form as: J Med Chem. 2007 Nov 16;50(25):6299–6302. doi: 10.1021/jm7011062

Table 1.

IC50 values of synthetic stereoisomers of laurenditerpenol.

Isomer Hypoxia (16 h) pHRE3-TK-luc[a]
1c 0.82 μM
1d 3.4 μM
ent-1g >30 μM
[a]

Values were obtained fromT47D cell-based reporter assay