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. 2010 Jun 3;59(8):1899–1905. doi: 10.2337/db10-0308

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© 2010 by the American Diabetes Association.

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FIG. 1. — Liver, muscle, and adipose tissue insulin sensitivity before (□) and after () 4 weeks of placebo or TUDCA treatment. A: Hepatic insulin sensitivity index. B: Glucose rate of disappearance (R_d); data represent only 8 of 10 subjects who received TUDCA treatment because of technical difficulties in obtaining blood samples in two subjects. C: Palmitate rate of appearance. Values are means ± SD. *Value significantly different from corresponding value before treatment, P < 0.05. †Main effect of insulin, P < 0.0001.

Inline graphic — Liver, muscle, and adipose tissue insulin sensitivity before (□) and after () 4 weeks of placebo or TUDCA treatment. A: Hepatic insulin sensitivity index. B: Glucose rate of disappearance (R_d); data represent only 8 of 10 subjects who received TUDCA treatment because of technical difficulties in obtaining blood samples in two subjects. C: Palmitate rate of appearance. Values are means ± SD. *Value significantly different from corresponding value before treatment, P < 0.05. †Main effect of insulin, P < 0.0001.