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. 2010 Jun 3;59(8):1899–1905. doi: 10.2337/db10-0308

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© 2010 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 1. — Liver, muscle, and adipose tissue insulin sensitivity before (□) and after () 4 weeks of placebo or TUDCA treatment. A: Hepatic insulin sensitivity index. B: Glucose rate of disappearance (R_d); data represent only 8 of 10 subjects who received TUDCA treatment because of technical difficulties in obtaining blood samples in two subjects. C: Palmitate rate of appearance. Values are means ± SD. *Value significantly different from corresponding value before treatment, P < 0.05. †Main effect of insulin, P < 0.0001.

Inline graphic — Liver, muscle, and adipose tissue insulin sensitivity before (□) and after () 4 weeks of placebo or TUDCA treatment. A: Hepatic insulin sensitivity index. B: Glucose rate of disappearance (R_d); data represent only 8 of 10 subjects who received TUDCA treatment because of technical difficulties in obtaining blood samples in two subjects. C: Palmitate rate of appearance. Values are means ± SD. *Value significantly different from corresponding value before treatment, P < 0.05. †Main effect of insulin, P < 0.0001.

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