Table 1.
Feature | All participants (N = 195) | Albendazole (N = 95) | Placebo (N = 100) | P value* |
---|---|---|---|---|
Age, median years (IQR) | 40 (29–53) | 39 (29–52) | 43 (28–53) | 0.6 |
Male gender, n (%) | 67 (34) | 26 (27) | 41 (41) | 0.05 |
Schooling, median years, (IQR) | 6 (3–10) | 6 (3–9) | 6 (4–10) | 0.4 |
Number of children in the household, median (IQR) | 4 (2–7) | 4 (2–7) | 4 (2–7) | 0.6 |
Anthropometry | ||||
Body mass index, median (IQR) | 23 (21–25) | 23 (21–25) | 23 (22–25) | 0.6 |
Percent body fat, median (IQR) | 30 (22–36) | 30 (20–36) | 31 (26–36) | 0.2 |
Living conditions | ||||
Earth floor, n (%) | 118/191 (62) | 65/93 (70) | 53/98 (54) | 0.07 |
River water source, n (%) | 99/191 (52) | 49/93 (53) | 50/98 (51) | 0.5 |
Lack of bathroom, n (%) | 93/191 (49) | 45/93 (48) | 48/98 (49) | 0.5 |
Socio-economics | ||||
Weekly money spent on food, median (IQR) | 20 (10–40) | 15 (10–35) | 20 (10–50) | 0.3 |
Food spending per day per person, median (IQR)† | 0.14 (0.06–0.34) | 0.12 (0.05–0.29) | 0.12 (0.06–0.36) | 0.2 |
Number of household residents, median (IQR) | 6 (4–8) | 6 (4–8) | 6 (4–8) | 0.9 |
Parasites history | ||||
Known past intestinal helminth infection, n (%) | 145/183 (80) | 69/90 (77) | 76/93 (82) | 0.4 |
Tuberculin skin test | ||||
Tuberculin skin-test size, median mm (IQR) | 9 (5–16) | 9 (5–16) | 9 (5–16) | 0.9 |
Tuberculin skin-test positivity (≥ 10 mm), n (%) | 85/174 (49) | 42/86 (49) | 41/88 (47) | 0.8 |
TB history | ||||
Known past TB disease, n (%) | 12/192 (6) | 5/94 (5) | 7/98 (7) | 0.8 |
Known past TB contact, n (%) | 34/191 (18) | 20/95 (21) | 14/96 (15) | 0.2 |
BCG | ||||
Absence of BCG scar, n (%) | 33/188 (18) | 18/92 (20) | 15/96 (16) | 0.5 |
One BCG scar, n (%) | 64/188 (34) | 34/92 (37) | 30/96 (31) | 0.4 |
Two or more BCG scar, n (%) | 91/188 (48) | 40/92 (43) | 51/96 (53) | 0.2 |
IQR = inter-quartile range; TB, tuberculosis.
Albendazole vs. placebo.
Money calculated in United States dollars.